Important Safety Information
Prescription TREXIMET is for acute treatment of migraine attacks in adults. TREXIMET may increase the risk of a heart attack, stroke, and serious stomach and intestinal problems such as bleeding and ulcers which may be fatal. Stomach and intestinal side effects may occur without warning. Do not take TREXIMET if you have a history of heart or liver disease, stroke, TIAs, problems with blood circulation, uncontrolled blood pressure, or allergic reaction to aspirin, NSAIDs, or sumatriptan. Talk to your doctor before taking TREXIMET if you have risk factors for heart disease, like smoking, diabetes, and high blood pressure; or have had stomach ulcers or bleeding, kidney problems; are pregnant, nursing, or thinking about becoming pregnant; or taking medications, especially pain relievers or antidepressants.