Important Safety Information
Prescribing Information (see boxed WARNINGS) and Medication Guide
TREXIMET may increase the risk of heart attack, stroke, serious stomach and intestinal problems such as bleeding and ulcers, and serious rash that may be fatal and occur without warning. Risk of stomach and intestinal problems increases in the elderly (see boxed WARNINGS). Continued Below
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discover your triggers
Many factors can come together to set a migraine in motion; including migraine triggers. These triggers can be external, like certain foods or changes in the weather, or even internal, such as hormonal changes before or after a menstrual period.
While some triggers are more common among migraine sufferers, your combination of triggers is going to be unique to your migraine situation. For example, you may discover that you can drink certain kinds of red wine as long as you are well rested, while other migraine sufferers will have to avoid red wine altogether.
You may never be able to identify all of the triggers that contribute to your migraines. But being on the lookout for your own personal triggers, using the migraine diary in My Tools to keep track of them, and discussing your triggers with your doctor, will be helpful when it comes to seeing the role that the triggers play in your migraines.
Visit My Community to get support that may help you deal with your migraines more effectively. You’ll hear real stories from others who suffer from migraines and learn how they’re dealing with their triggers every day.
next: get migraine tips
myth or reality?
You can’t control all your migraine triggers.
This is true.
Every person's triggers may be different. Even the best efforts at controlling triggers may not be enough to prevent the occurrence of migraines. However, the more you know about your own triggers, the easier it may be to plan ahead.
Learn more.
Prescription TREXIMET is for the acute treatment of migraine attacks in adults.
Important Safety Information About TREXIMET
TREXIMET may increase the risk of heart attack, stroke, serious stomach and intestinal problems such as bleeding and ulcers, and serious rash that may be fatal and occur without warning. Risk of stomach and intestinal problems increases in the elderly.
Do not take TREXIMET if you have a history of heart or liver disease, stroke, TIAs, problems with blood circulation, uncontrolled blood pressure, or allergic reaction to aspirin, NSAIDs, or sumatriptan (Imitrex®); or right before or after heart surgery called coronary artery bypass graft (CABG).
Talk to your doctor before taking TREXIMET if you have risk factors for heart disease like high blood pressure, high cholesterol, smoking, obesity, diabetes, family history of heart disease, are a post-menopausal female, or male over age 40.
Talk to your doctor before taking TREXIMET if you have stomach ulcers or bleeding; chest pain, shortness of breath, irregular heartbeats; kidney problems; asthma; Crohn's disease or ulcerative colitis; are pregnant, nursing, or thinking about becoming pregnant; or taking medications, especially pain relievers or antidepressants. TREXIMET should not be used in late pregnancy (third trimester) because TREXIMET can harm your unborn baby. TREXIMET should not be used if you are breastfeeding or plan to breastfeed because TREXIMET passes into your breast milk and may harm your baby. Serotonin syndrome, a life-threatening problem, may occur with TREXIMET, especially if used with antidepressants called SSRIs or SNRIs. Do not take TREXIMET if you have taken an MAOI antidepressant within the last 2 weeks. Do not take TREXIMET if you have taken ergotamine-containing medicines or other triptans within the last 24 hours. TREXIMET should only be used exactly as prescribed, at the lowest dose and for the shortest time possible.
Some people who take TREXIMET too often may have worse headaches. If your headaches get worse, your doctor may stop treatment with TREXIMET. Your doctor may encourage you to track your headache frequency and medication use.