Prescribing Information (see boxed WARNINGS) and Medication Guide
TREXIMET may increase the risk of heart attack, stroke, serious stomach and intestinal problems such as bleeding and ulcers, and serious rash that may be fatal and occur without warning. Risk of stomach and intestinal problems increases in the elderly (see boxed WARNINGS). Continued Below
Even those who have been living with migraines for a while can be unsure about the symptoms they are experiencing—which means they might wait to take their migraine medication until it gets "really bad." But if you wait until symptoms get worse to treat a migraine, your attack could become more severe. Knowing more about symptoms may help you manage migraines when they occur and that may help you keep them from getting worse.
Use the model below to become more familiar with the symptoms of a migraine. If you’re experiencing one or more of these symptoms, no matter how mild, it’s important to talk to your doctor about them. And of course, treat your migraines as instructed by your doctor.
Aside from the symptoms you feel during your migraine attack, some people may experience signs that a migraine attack is on its way. My Tools can help you become more familiar with your personal signs, which may include food cravings, mood changes, yawning, fatigue, flashing lights or wavy lines, numbness, tingling in the face, and disturbed senses.
next: discover your triggers
Migraines can run in your family.
This is true.
Migraines can be hereditary. If one of your close relatives suffers from migraines, you may be at risk for developing migraine.
Prescription TREXIMET is for the acute treatment of migraine attacks in adults.
TREXIMET may increase the risk of heart attack, stroke, serious stomach and intestinal problems such as bleeding and ulcers, and serious rash that may be fatal and occur without warning. Risk of stomach and intestinal problems increases in the elderly.
Do not take TREXIMET if you have a history of heart or liver disease, stroke, TIAs, problems with blood circulation, uncontrolled blood pressure, or allergic reaction to aspirin, NSAIDs, or sumatriptan (Imitrex®); or right before or after heart surgery called coronary artery bypass graft (CABG).
Talk to your doctor before taking TREXIMET if you have risk factors for heart disease like high blood pressure, high cholesterol, smoking, obesity, diabetes, family history of heart disease, are a post-menopausal female, or male over age 40.
Talk to your doctor before taking TREXIMET if you have stomach ulcers or bleeding; chest pain, shortness of breath, irregular heartbeats; kidney problems; asthma; Crohn's disease or ulcerative colitis; are pregnant, nursing, or thinking about becoming pregnant; or taking medications, especially pain relievers or antidepressants. TREXIMET should not be used in late pregnancy (third trimester) because TREXIMET can harm your unborn baby. TREXIMET should not be used if you are breastfeeding or plan to breastfeed because TREXIMET passes into your breast milk and may harm your baby. Serotonin syndrome, a life-threatening problem, may occur with TREXIMET, especially if used with antidepressants called SSRIs or SNRIs. Do not take TREXIMET if you have taken an MAOI antidepressant within the last 2 weeks. Do not take TREXIMET if you have taken ergotamine-containing medicines or other triptans within the last 24 hours. TREXIMET should only be used exactly as prescribed, at the lowest dose and for the shortest time possible.
Some people who take TREXIMET too often may have worse headaches. If your headaches get worse, your doctor may stop treatment with TREXIMET. Your doctor may encourage you to track your headache frequency and medication use.